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GTX57665

QPRT antibody [AT24C4]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX57665
Zusätzliche Namen:
quinolinate phosphoribosyltransferase , HELS90n , QPRT , QPRTase
Anwendung:
WB, IF, ICC
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human
Buffer:
PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:
The clone AT24C4 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human QPRT protein.
Klon:
AT24C4
Uniprot:
Q15274
Synonyme:
epididymis secretory sperm binding protein Li 90n;HEL-S-90n;nicotinate-nucleotide pyrophosphorylase (carboxylating);nicotinate-nucleotide pyrophosphorylase [carboxylating];QPRTase;Quinolinate phosphoribosyltransferase [decarboxylating]
Weitere Details:
This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Versandbedingungen:
Blue Ice