RAIDD antibody [AT14G8]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX57605
Zusätzliche Namen:: CASP2 and RIPK1 domain containing adaptor with death domain , CRADD , MRT34 , RAIDD
Anwendung:: WB, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:: The clone AT14G8 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CRADD protein.
Klon:: AT14G8
Uniprot:: P78560
Synonyme:: Caspase and RIP adapter with death domain;caspase and RIP adaptor with death domain;CRADD/LYZ fusion;death adaptor molecule RAIDD;death domain containing protein CRADD;death domain-containing protein CRADD;MRT34;RAIDD;RIP-associated ICH1/CED3-homologous protein with death domain;RIP-associated protein with a death domain
Weitere Details:: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]

Versandbedingungen:: Blue Ice