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GTX57593

Diablo antibody [AT19F2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX57593
Zusätzliche Namen:
diablo IAP-binding mitochondrial protein , DFNA64 , DIABLO , SMAC , diablo IAPbinding mitochondrial protein , Smac , Diablo
Anwendung:
Flow Cytometry, WB, IF, ICC
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein A Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human
Buffer:
PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:
The clone AT19F2 is derived from hybridization of mouse F2 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SMAC/Diablo protein.
Klon:
AT19F2
Uniprot:
Q9NR28
Synonyme:
DFNA64;diablo homolog, mitochondrial;diablo-like protein;direct IAP-binding protein with low pI;second mitochondria-derived activator of caspase;SMAC
Weitere Details:
This gene encodes an inhibitor of apoptosis protein (IAP)-binding protein. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Versandbedingungen:
Blue Ice