eIF2 alpha antibody [5E10]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX57580
Zusätzliche Namen:: eukaryotic translation initiation factor 2 subunit alpha , EIF2 , EIF2A , EIF2S1 , EIF2alpha , eIF2 alpha
Anwendung:: WB, IF, ICC
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human, Mouse
Buffer:: PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:: The clone 5E10 is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human EIF2S3 protein.
Klon:: 5E10
Uniprot:: P05198
Synonyme:: EIF-2;eIF-2-alpha;EIF-2A;EIF-2alpha;EIF2;EIF2A;eukaryotic translation initiation factor 2 subunit 1;Eukaryotic translation initiation factor 2 subunit alpha;eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
Weitere Details:: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010]

Versandbedingungen:: Blue Ice