GTX57405-PRO
Human SELH protein, His tag
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX57405-PRO
- Zusätzliche Namen:
- selenoprotein H , C11orf31 , C17orf10 , SELH
- Konzentration:
- 0.5 mg/ml
- Physischer Zustand:
- Liquid
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Buffer:
- 20mM Tris-HCl, 150mM NaCl, 20% Glycerol, 1mM DTT, no preservatives.
- Immunogen:
- selenoprotein H
- Spezies:
- Human
- Uniprot:
- Q8IZQ5
- Synonyme:
- C11orf31;C17orf10;selenoprotein H;SELH
- Weitere Details:
- This gene encodes a nucleolar protein, which belongs to the SelWTH family. It functions as an oxidoreductase, and has been shown to protect neurons against UVB-induced damage by inhibiting apoptotic cell death pathways, promote mitochondrial biogenesis and mitochondrial function, and suppress cellular senescence through genome maintenance and redox regulation. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2016]
- Versandbedingungen:
- Dry Ice