Human DPH4 protein, His tag

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX57310-PRO
Zusätzliche Namen:: DnaJ heat shock protein family (Hsp40) member C24 , DPH4 , JJJ3 , ZCSL3
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Buffer:: 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, 1mM DTT, no preservatives.
Immunogen:: DnaJ heat shock protein family (Hsp40) member C24
Spezies:: Human
Uniprot:: Q6P3W2
Synonyme:: 1700030A21Rik;CSL-type zinc finger-containing protein 3;diphthamide biosynthesis protein 4;DnaJ (Hsp40) homolog, subfamily C, member 24;dnaJ homolog subfamily C member 24;DPH4;DPH4 homolog (JJJ3, S. cerevisiae);DPH4, JJJ3 homolog;JJJ3;ZCSL3;zinc finger, CSL domain containing 3;zinc finger, CSL-type containing 3
Weitere Details:: Diphthamide is a unique posttranslationally modified histidine found only in translation elongation factor-2 (EEF2; MIM 130610). This modification is conserved from archaebacteria to humans and serves as the target for ADP-ribosylation and inactivation of EEF2 by diphtheria toxin (DT) and Pseudomonas exotoxin A. DPH4 is 1 of several enzymes involved in synthesis of diphthamide in EEF2 (Liu et al., 2004 [PubMed 15485916]).[supplied by OMIM, Mar 2008]