p53 antibody [IHC053]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX57208
Zusätzliche Namen:: Tumor Protein P53 , Bcc7 , Lfs1 , P53 , Trp53 , Tp53
Anwendung:: IHC-P
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: 2-8[o]C Do not freeze.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: Tris, 1% BSA, 0.09% Sodium azide.
Immunogen:: Recombinant Human p53 protein.
Klon:: IHC053
Synonyme:: antigen NY-CO-13;BCC7;BMFS5;cellular tumor antigen p53;LFS1;mutant tumor protein 53;P53;p53 tumor suppressor;phosphoprotein p53;transformation-related protein 53;TRP53;tumor protein 53;tumor supressor p53
Weitere Details:: This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013]