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GTX57187

MLH1 antibody [IHC409]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX57187
Zusätzliche Namen:
Mutl Homolog 1 , Coca2 , Fcc2 , Hnpcc , Hnpcc2 , Hmlh1 , Mlh1
Anwendung:
IHC-P
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein A Purified
Lagerbedingungen:
2-8[o]C Do not freeze.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human
Buffer:
Tris, 1% BSA, 0.09% Sodium azide.
Immunogen:
Recombinant Human MLH1 protein.
Klon:
IHC409
Synonyme:
COCA2;DNA mismatch repair protein Mlh1;FCC2;hMLH1;HNPCC;HNPCC2;MMRCS1;mutL homolog 1, colon cancer, nonpolyposis type 2
Weitere Details:
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.[provided by RefSeq, Nov 2009]
Versandbedingungen:
Blue Ice