![COL4A1 antibody [IHC549]](https://www.genetex.com/upload/website/prouct_img/normal/GTX57183/GTX57183_20180619_IHC-P_w_23061123_444.webp)
GTX57183
COL4A1 antibody [IHC549]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX57183
- Zusätzliche Namen:
- Collagen Type Iv Alpha 1 Chain , Bsvd , Rator , Col4A1
- Anwendung:
- IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein A Purified
- Lagerbedingungen:
- 2-8[o]C Do not freeze.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- Tris, 1% BSA, 0.09% Sodium azide.
- Immunogen:
- Human Placenta protein.
- Klon:
- IHC549
- Synonyme:
- arresten;BSVD;BSVD1;COL4A1 NC1 domain;COL4A1s;collagen alpha-1(IV) chain;collagen IV, alpha-1 polypeptide;collagen of basement membrane, alpha-1 chain;PADMAL;RATOR
- Weitere Details:
- This gene encodes a type IV collagen alpha protein. Type IV collagen proteins are integral components of basement membranes. This gene shares a bidirectional promoter with a paralogous gene on the opposite strand. The protein consists of an amino-terminal 7S domain, a triple-helix forming collagenous domain, and a carboxy-terminal non-collagenous domain. It functions as part of a heterotrimer and interacts with other extracellular matrix components such as perlecans, proteoglycans, and laminins. In addition, proteolytic cleavage of the non-collagenous carboxy-terminal domain results in a biologically active fragment known as arresten, which has anti-angiogenic and tumor suppressor properties. Mutations in this gene cause porencephaly, cerebrovascular disease, and renal and muscular defects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
- Versandbedingungen:
- Blue Ice