GTX56285
Cytochrome P450 2C9 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX56285
- Zusätzliche Namen:
- cytochrome P450 family 2 subfamily C member 9 , CPC9 , CYP2C , CYP2C10 , CYPIIC9 , P450IIC9
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
- Immunogen:
- KLH-conjugated synthetic peptide encompassing a sequence within the center region of Cytochrome P450 2C9. The exact sequence is proprietary.
- Uniprot:
- P11712
- Synonyme:
- (R)-limonene 6-monooxygenase;(S)-limonene 6-monooxygenase;(S)-limonene 7-monooxygenase;Cholesterol 25-hydroxylase;CPC9;CYP2C;CYP2C10;CYPIIC9;cytochrome P-450 S-mephenytoin 4-hydroxylase;cytochrome P-450MP;cytochrome P450 2C9;Cytochrome P450 MP-4;Cytochrome P450 MP-8;cytochrome P450 PB-1;cytochrome P450, family 2, subfamily C, polypeptide 9;flavoprotein-linked monooxygenase;microsomal monooxygenase;P450IIC9;S-mephenytoin 4-hydroxylase;xenobiotic monooxygenase
- Weitere Details:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice