CYP2B6 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX56284
Zusätzliche Namen:: cytochrome P450 family 2 subfamily B member 6 , CPB6 , CYP2B , CYP2B7 , CYP2B7P , CYPIIB6 , EFVM , IIB1 , P450
Anwendung:: WB, IHC-P, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
Immunogen:: KLH-conjugated synthetic peptide encompassing a sequence within the center region of CYP2B6. The exact sequence is proprietary.
Uniprot:: P20813
Synonyme:: 1,4-cineole 2-exo-monooxygenase;CPB6;CYP2B;CYP2B7;CYP2B7P;CYPIIB6;cytochrome P450 2B6;cytochrome P450 IIB1;cytochrome P450, family 2, subfamily B, polypeptide 6;cytochrome P450, subfamily IIB (phenobarbital-inducible), polypeptide 6;EFVM;IIB1;P450
Weitere Details:: This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice