GPX2 antibody, Internal

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX56140
Zusätzliche Namen:: glutathione peroxidase 2 , GI-GPx , GPRP , GPRP-2 , GPx-2 , GPx-GI , GSHPX-GI , GSHPx-2
Anwendung:: WB
Konzentration:: 0.50 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Ammonium Sulfate Precipitated; Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Goat
Reaktivitäten:: Human
Buffer:: TBS, 0.5% BSA, 0.02% Sodium azide.
Immunogen:: Peptide with sequence C-SLDGEKVDFN, from the internal region of the protein sequence according to NP_002074.2.
Uniprot:: P18283
Synonyme:: gastrointestinal glutathione peroxidase;GI-GPx;glutathione peroxidase 2;glutathione peroxidase 2 (gastrointestinal);Glutathione peroxidase-gastrointestinal;glutathione peroxidase-related protein 2;GPRP;GPRP-2;GPx-2;GPx-GI;GSHPx-2;GSHPX-GI;selenoprotein GPX2
Weitere Details:: The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of organic hydroperoxides and hydrogen peroxide (H2O2) by glutathione, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme is predominantly expressed in the gastrointestinal tract (also in liver in human), is localized in the cytoplasm, and whose preferred substrate is hydrogen peroxide. Overexpression of this gene is associated with increased differentiation and proliferation in colorectal cancer. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2016]

Versandbedingungen:: Blue Ice