GTX55997
Pericentrin antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55997
- Zusätzliche Namen:
- pericentrin , KEN , MOPD2 , PCN , PCNT2 , PCNTB , PCTN2 , SCKL4
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
- Immunogen:
- KLH-conjugated synthetic peptide encompassing a sequence within the center region of Pericentrin. The exact sequence is proprietary.
- Uniprot:
- O95613
- Synonyme:
- KEN;kendrin;MOPD2;PCN;PCNT2;PCNTB;PCTN2;pericentrin;pericentrin-2;pericentrin-380;pericentrin-B;SCKL4
- Weitere Details:
- The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM). The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
- Versandbedingungen:
- Blue Ice