Surfactant Protein B antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX55891
Zusätzliche Namen:: surfactant protein B , PSP-B , SFTB3 , SFTP3 , SMDP1 , SP-B
Anwendung:: WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
Immunogen:: KLH-conjugated synthetic peptide encompassing a sequence within the center region of Surfactant Protein B. The exact sequence is proprietary.
Uniprot:: P07988
Synonyme:: 18 kDa pulmonary-surfactant protein;6 kDa protein;PSP-B;pulmonary surfactant-associated protein B;pulmonary surfactant-associated proteolipid SPL(Phe);SFTB3;SFTP3;SMDP1;SP-B
Weitere Details:: This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010]

Versandbedingungen:: Blue Ice