GTX55885
PTPRN2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55885
- Zusätzliche Namen:
- protein tyrosine phosphatase receptor type N2 , IA-2beta , IAR , ICAAR , PTPRP , R-PTP-N2
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
- Immunogen:
- KLH-conjugated synthetic peptide encompassing a sequence within the center region of PTPRN2. The exact sequence is proprietary.
- Uniprot:
- Q92932
- Synonyme:
- IA-2beta;IAR;IAR/receptor-like protein-tyrosine phosphatase;ICAAR;islet cell autoantigen-related protein;phogrin;protein tyrosine phosphatase receptor pi;protein tyrosine phosphatase, receptor type, N polypeptide 2;PTPRP;R-PTP-N2;receptor-type tyrosine-protein phosphatase N2;tyrosine phosphatase IA-2 beta
- Weitere Details:
- This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
- Versandbedingungen:
- Blue Ice