GTX55845
XPC antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55845
- Zusätzliche Namen:
- XPC complex subunit, DNA damage recognition and repair factor , RAD4 , XP3 , XPCC , p125
- Anwendung:
- WB, IHC-P, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 700-940 of human XPC (NP_004619.3).
- Uniprot:
- Q01831
- Synonyme:
- DNA repair protein complementing XP-C cells;mutant xeroderma pigmentosum group C;p125;RAD4;Xeroderma pigmentosum group C-complementing protein;xeroderma pigmentosum, complementation group C;XP3;XPCC
- Weitere Details:
- The protein encoded by this gene is a key component of the XPC complex, which plays an important role in the early steps of global genome nucleotide excision repair (NER). The encoded protein is important for damage sensing and DNA binding, and shows a preference for single-stranded DNA. Mutations in this gene or some other NER components can result in Xeroderma pigmentosum, a rare autosomal recessive disorder characterized by increased sensitivity to sunlight with the development of carcinomas at an early age. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017]
- Versandbedingungen:
- Blue Ice