GTX55742
PDI antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55742
- Zusätzliche Namen:
- prolyl 4-hydroxylase subunit beta , CLCRP1 , DSI , ERBA2L , GIT , P4Hbeta , PDI , PDIA1 , PHDB , PO4DB , PO4HB , PROHB
- Anwendung:
- WB, IF, ICC, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 329-508 of human P4HB (NP_000909.2).
- Uniprot:
- P07237
- Synonyme:
- cellular thyroid hormone-binding protein;CLCRP1;collagen prolyl 4-hydroxylase beta;DSI;ERBA2L;GIT;glutathione-insulin transhydrogenase;P4Hbeta;p55;PDI;PDIA1;PHDB;PO4DB;PO4HB;procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide;PROHB;Prolyl 4-hydroxylase subunit beta;prolyl 4-hydroxylase, beta polypeptide;protein disulfide isomerase family A, member 1;protein disulfide isomerase-associated 1;protein disulfide isomerase/oxidoreductase;protein disulfide-isomerase;protocollagen hydroxylase;testicular secretory protein Li 32;thyroid hormone-binding protein p55
- Weitere Details:
- This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice