GTX55683
Jab1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55683
- Zusätzliche Namen:
- COP9 signalosome subunit 5 , CSN5 , JAB1 , MOV-34 , SGN5
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-334 of human COPS5 (NP_006828.2).
- Uniprot:
- Q92905
- Synonyme:
- 38 kDa Mov34 homolog;COP9 constitutive photomorphogenic homolog subunit 5;COP9 signalosome complex subunit 5;CSN5;JAB1;jun activation domain-binding protein 1;MOV-34;SGN5;signalosome subunit 5;testis secretory sperm-binding protein Li 231m
- Weitere Details:
- The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice