GTX55676
IL1 Receptor 2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55676
- Zusätzliche Namen:
- interleukin 1 receptor type 2 , CD121b , CDw121b , IL-1R-2 , IL-1RT-2 , IL-1RT2 , IL1R2c , IL1RB
- Anwendung:
- WB
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 20-320 of human IL1R2 (NP_775465.1).
- Uniprot:
- P27930
- Synonyme:
- antigen CDw121b;CD121 antigen-like family member B;CD121b;CDw121b;IL-1 type II receptor;IL-1R-2;IL-1R-beta;IL-1RT-2;IL-1RT2;IL1R2c;IL1RB;interleukin 1 receptor type II variant 3;interleukin-1 receptor beta;interleukin-1 receptor type 2;interleukin-1 receptor type II;type II interleukin-1 receptor, beta
- Weitere Details:
- The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. This gene and three other genes form a cytokine receptor gene cluster on chromosome 2q12. Alternative splicing results in multiple transcript variants and protein isoforms. Alternative splicing produces both membrane-bound and soluble proteins. A soluble protein is also produced by proteolytic cleavage. [provided by RefSeq, May 2012]
- Versandbedingungen:
- Blue Ice