GTX55625
FKBP25 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55625
- Zusätzliche Namen:
- FKBP prolyl isomerase 3 , FKBP-25 , FKBP-3 , FKBP25 , PPIase
- Anwendung:
- WB, IF, ICC, IP
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-224 of human FKBP3 (NP_002004.1).
- Uniprot:
- Q00688
- Synonyme:
- 25 kDa FK506-binding protein;25 kDa FKBP;FK506 binding protein 3, 25kDa;FK506-binding protein 25, T-cell;FK506-binding protein 3;FKBP-25;FKBP-3;FKBP25;immunophilin FKBP25;peptidyl-prolyl cis-trans isomerase FKBP3;PPIase;PPIase FKBP3;rapamycin binding protein;rapamycin-selective 25 kDa immunophilin;rotamase
- Weitere Details:
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq, Sep 2008]
- Versandbedingungen:
- Blue Ice