GTX55571
CHRFAM7A antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55571
- Zusätzliche Namen:
- CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion , CHRNA7 , CHRNA7-DR1 , D-10 , NACHRA7
- Anwendung:
- IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CHRFAM7A (NP_647536.1).
- Uniprot:
- P36544, Q494W8
- Synonyme:
- a7 nicotinic acetylcholine receptor;alpha 7 neuronal nicotinic acetylcholine receptor;alpha 7 neuronal nicotinic acetylcholine receptor-FAM7A hybrid;alpha-7 nicotinic cholinergic receptor subunit;cholinergic receptor, nicotinic alpha 7;cholinergic receptor, nicotinic, alpha 7 (neuronal);cholinergic receptor, nicotinic, alpha polypeptide 7;CHRNA7;CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion;CHRNA7 (cholinergic receptor, nicotinic, alpha polypeptide 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion;CHRNA7-2;CHRNA7-DR1;CHRNA7-FAM7A fusion protein;D-10;NACHRA7;neuronal acetylcholine receptor protein, alpha-7 chain;neuronal acetylcholine receptor subunit alpha-7
- Weitere Details:
- The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice