GTX55450
UBTF (phospho Ser484) antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55450
- Zusätzliche Namen:
- upstream binding transcription factor , CONDBA , NOR-90 , UBF , UBF-1 , UBF1 , UBF2
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Peptide sequence around phosphorylation site of serine 484 (P-E-S(p)-P-K) derived from human UBTF.
- Uniprot:
- P17480
- Synonyme:
- 90-kDa nucleolus organizer region autoantigen;autoantigen NOR-90;CONDBA;NOR-90;nucleolar transcription factor 1;UBF;UBF-1;UBF1;UBF2;upstream binding transcription factor, RNA polymerase I;Upstream-binding factor 1
- Weitere Details:
- This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]
- Versandbedingungen:
- Blue Ice