GTX55349
C/EBP alpha (phospho Thr230) antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55349
- Zusätzliche Namen:
- CCAAT enhancer binding protein alpha , C/EBP-alpha , CEBP
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Peptide sequence around phosphorylation site of threonine 230 (P-P-T(p)-P-V) derived from human C/EBP alpha.
- Uniprot:
- P49715
- Synonyme:
- C/EBP-alpha;CCAAT/enhancer binding protein (C/EBP), alpha;CCAAT/enhancer-binding protein alpha;CEBP
- Weitere Details:
- This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. [provided by RefSeq, Dec 2013]
- Versandbedingungen:
- Blue Ice