GTX55348
APLP2 (phospho Tyr755) antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55348
- Zusätzliche Namen:
- amyloid beta precursor like protein 2 , APLP-2 , APPH , APPL2 , CDEBP
- Anwendung:
- IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Peptide sequence around phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y) derived from human APLP2.
- Uniprot:
- Q06481
- Synonyme:
- amyloid beta (A4) precursor-like protein 2;amyloid precursor protein homolog HSD-2;Amyloid protein homolog;amyloid-like protein 2;APLP-2;APPH;APPL2;CDEBP;CDEI box-binding protein;testicular tissue protein Li 23
- Weitere Details:
- This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
- Versandbedingungen:
- Blue Ice