GTX55291
UBR1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55291
- Zusätzliche Namen:
- ubiquitin protein ligase E3 component n-recognin 1 , JBS
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
- Immunogen:
- KLH-conjugated synthetic peptide encompassing a sequence within the center region of UBR1. The exact sequence is proprietary.
- Uniprot:
- Q8IWV7
- Synonyme:
- E3 ubiquitin-protein ligase UBR1;E3a ligase;JBS;N-recognin-1;RING-type E3 ubiquitin transferase UBR1;ubiquitin ligase E3 alpha-I;ubiquitin-protein ligase E3-alpha;ubiquitin-protein ligase E3-alpha-1;ubiquitin-protein ligase E3-alpha-I
- Weitere Details:
- The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice