COX17 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX55188
Zusätzliche Namen:: cytochrome c oxidase copper chaperone COX17
Anwendung:: WB, IHC-P, IF, ICC
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
Immunogen:: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of COX17. The exact sequence is proprietary.
Uniprot:: Q14061
Synonyme:: COX17 cytochrome c oxidase assembly homolog;COX17, cytochrome c oxidase copper chaperone;cytochrome c oxidase 17 copper chaperone;cytochrome c oxidase assembly homolog 17;cytochrome c oxidase copper chaperone;human homolog of yeast mitochondrial copper recruitment
Weitere Details:: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be involved in the recruitment of copper to mitochondria for incorporation into the COX apoenzyme. This protein shares 92% amino acid sequence identity with mouse and rat Cox17 proteins. This gene is no longer considered to be a candidate gene for COX deficiency. A pseudogene COX17P has been found on chromosome 13. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice