GTX55164
MED1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX55164
- Zusätzliche Namen:
- mediator complex subunit 1 , CRSP1 , CRSP200 , DRIP205 , DRIP230 , PBP , PPARBP , PPARGBP , RB18A , TRAP220 , TRIP2
- Anwendung:
- WB, IHC-P, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
- Immunogen:
- KLH-conjugated synthetic peptide encompassing a sequence within the center region of MED1. The exact sequence is proprietary.
- Uniprot:
- Q15648
- Synonyme:
- activator-recruited cofactor 205 kDa component;ARC205;CRSP1;CRSP200;DRIP205;DRIP230;Mediator complex subunit 1;mediator of RNA polymerase II transcription subunit 1;p53 regulatory protein RB18A;PBP;peroxisome proliferator-activated receptor-binding protein;PPAR-binding protein;PPARBP;PPARG binding protein;PPARGBP;RB18A;thyroid hormone receptor-associated protein complex 220 kDa component;thyroid hormone receptor-associated protein complex component TRAP220;thyroid receptor interacting protein 2;Thyroid receptor-interacting protein 2;TR-interacting protein 2;TRAP220;TRIP-2;TRIP2;vitamin D receptor-interacting protein 230 kD;vitamin D receptor-interacting protein complex component DRIP205
- Weitere Details:
- The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. It also regulates p53-dependent apoptosis and it is essential for adipogenesis. This protein is known to have the ability to self-oligomerize. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice