ILF3 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX55155
Zusätzliche Namen:: interleukin enhancer binding factor 3 , CBTF , DRBF , DRBP76 , MMP4 , MPHOSPH4 , MPP4 , NF-AT-90 , NF110 , NF110b , NF90 , NF90a , NF90b , NFAR , NFAR-1 , NFAR2 , TCP110 , TCP80
Anwendung:: WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: 0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol, 0.01% Sodium azide.
Immunogen:: KLH-conjugated synthetic peptide encompassing a sequence within the center region of ILF3. The exact sequence is proprietary.
Uniprot:: Q12906
Synonyme:: CBTF;Double-stranded RNA-binding protein 76;double-stranded RNA-binding protein, 76 kD;DRBF;DRBP76;dsRNA binding protein NFAR-2/MPP4;interleukin enhancer binding factor 3, 90kD;interleukin enhancer binding factor 3, 90kDa;interleukin enhancer-binding factor 3;M phase phosphoprotein 4, nuclear factor associated with DS RNA;M-phase phosphoprotein 4;MMP4;MPHOSPH4;MPP4;MPP4110;NF-AT-90;NF110;NF110b;NF90;NF90a;NF90b;NF90c;NF90ctv;NFAR;NFAR-1;NFAR-2;NFAR110;NFAR2;NFAR90;nuclear factor associated with dsRNA;nuclear factor of activated T-cells 110 kDa;nuclear factor of activated T-cells 90 kDa;nuclear factor of activated T-cells, 90 kD;TCP110;TCP80;translational control protein 80
Weitere Details:: This gene encodes a double-stranded RNA (dsRNA) binding protein that complexes with other proteins, dsRNAs, small noncoding RNAs, and mRNAs to regulate gene expression and stabilize mRNAs. This protein (NF90, ILF3) forms a heterodimer with a 45 kDa transcription factor (NF45, ILF2) required for T-cell expression of interleukin 2. This complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. In contrast, an isoform (NF110) of this gene that is predominantly restricted to the nucleus has only minor effects on cell growth when its levels are reduced. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2014]

Versandbedingungen:: Blue Ice