GTX54797
Nav1.2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX54797
- Zusätzliche Namen:
- sodium voltage-gated channel alpha subunit 2 , NachII , Nav1.2 , RII/RIIA , RNSCPIIR , SCN , Scn2a1 , Scn2a2 , ScpII
- Anwendung:
- WB, IHC-Fr, IF, ICC, IP
- Konzentration:
- 0.8 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Rat
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 1% BSA, 0.05% Sodium azide.
- Immunogen:
- Peptide (C)ASAESRDFSGAGGIGVFSE, corresponding to amino acid residues 467-485 (Intracellular loop between domains I and II) of rat NaV1.2 (Accession : P04775).
- Uniprot:
- P04775
- Synonyme:
- NachII;Nav1.2;RII/RIIA;RIIA sodium channel protein;RNSCPIIR;SCN;Scn2a1;Scn2a2;ScpII;Sodium channel protein brain II subunit alpha;sodium channel protein type 2 subunit alpha;sodium channel protein type II subunit alpha;sodium channel protein, brain II subunit alpha;sodium channel voltage-gated type II alpha polypeptide;sodium channel, voltage-gated, type 2, alpha 1 polypeptide;sodium channel, voltage-gated, type 2, alpha 1 subunit;sodium channel, voltage-gated, type II, alpha 1;sodium channel, voltage-gated, type II, alpha subunit;voltage-gated sodium channel subunit alpha Nav1.2
- Weitere Details:
- Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with four repeat domains, each of which is composed of six membrane-spanning segments, and one or more regulatory beta subunits. Voltage-gated sodium channels are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family. In humans, variants of this gene are associated with seizure disorders and autism spectrum disorder. Mice homozygous for a knockout mutation die with severe hypoxia and extensive neuronal cell death, while gain of function mutations result in progressive seizure disorder. [provided by RefSeq, Nov 2016]
- Versandbedingungen:
- Blue Ice