GTX54696
RASSF1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX54696
- Zusätzliche Namen:
- Ras association domain family member 1 , 123F2 , NORE2A , RASSF1A , RDA32 , REH3P21
- Anwendung:
- WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 101-340 of human RASSF1 (NP_009113.3).
- Uniprot:
- Q9NS23
- Synonyme:
- 123F2;cardiac-specific ras association domain family 1 protein;NORE2A;pancreas-specific ras association domain family 1 protein;Ras association (RalGDS/AF-6) domain family member 1;ras association domain-containing protein 1;RASSF1A;RDA32;REH3P21;tumor suppressor protein RDA32;WUGSC:H_LUCA12.5
- Weitere Details:
- This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers, which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1, and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, May 2011]
- Versandbedingungen:
- Blue Ice