GTX54611
PRG2 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX54611
- Zusätzliche Namen:
- proteoglycan 2, pro eosinophil major basic protein , BMPG , MBP , MBP1 , proMBP
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 17-222 of human PRG2 (NP_002719.3).
- Uniprot:
- P13727
- Synonyme:
- BMPG;bone marrow proteoglycan;eosinophil granule major basic protein;eosinophil major basic protein;MBP;MBP1;natural killer cell activator;proMBP;Proteoglycan 2;proteoglycan 2 preproprotein;proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein)
- Weitere Details:
- The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. The encoded protein contains a peptide that displays potent antimicrobial activity against Gram-positive bacteria, Gram-negative bacteria, and fungi. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]
- Versandbedingungen:
- Blue Ice