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  2. Polyclonal

GTX54092

HSD3B2 antibody

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX54092
Zusätzliche Namen:
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 , HSD3B , HSDB , SDR11E2
Anwendung:
WB, IF, ICC
Konzentration:
1 mg/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
PBS, 50% Glycerol, 0.02% Sodium azide.
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human HSD3B2 (NP_000189.1).
Uniprot:
P26439
Synonyme:
3 beta-HSD type II;3 beta-hydroxysteroid dehydrogenase type II, delta 5-delta 4-isomerase type II, 3 beta-HSD type II;3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2;3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type II;3-beta-HSD adrenal and gonadal type;3-beta-HSD II;3-beta-hydroxy-5-ene steroid dehydrogenase;3-beta-hydroxy-Delta(5)-steroid dehydrogenase;delta 5-delta 4-isomerase type II;HSD3B;HSDB;progesterone reductase;SDR11E2;short chain dehydrogenase/reductase family 11E, member 2
Weitere Details:
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
Versandbedingungen:
Blue Ice