GTX53996
Fumarate hydratase antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX53996
- Zusätzliche Namen:
- fumarate hydratase , FMRD , HLRCC , LRCC , MCL , MCUL1
- Anwendung:
- WB, IF, ICC
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human FH (NP_000134.2).
- Uniprot:
- P07954
- Synonyme:
- epididymis secretory sperm binding protein;FMRD;fumarase;fumarate hydratase, mitochondrial;HLRCC;HsFH;LRCC;MCL;MCUL1
- Weitere Details:
- The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice