Creatine kinase MT antibody [AT17A2]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX53700
Zusätzliche Namen:: creatine kinase, mitochondrial 1A , CKMT1 , U-MtCK , mia-CK
Anwendung:: ELISA, WB
Konzentration:: 1 mg/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein A Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 10% Glycerol, 0.02% Sodium azide.
Immunogen:: Recombinant human CKMT1A (40-417aa) purified from E. coli
Klon:: AT17A2
Uniprot:: P12532
Synonyme:: acidic-type mitochondrial creatine kinase;CKMT;CKMT1;creatine kinase U-type, mitochondrial;creatine kinase, mitochondrial 1 (ubiquitous);mia-CK;U-MtCK;ubiquitous mitochondrial creatine kinase;UMTCK
Weitere Details:: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice