GTX53514
COL9A1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX53514
- Zusätzliche Namen:
- collagen type IX alpha 1 chain , DJ149L1.1.2 , EDM6 , MED , STL4
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- KLH conjugated synthetic peptide between 428-456 amino acids from the Central region of human COL9A1.
- Uniprot:
- P20849
- Synonyme:
- alpha-1(IX) collagen chain;cartilage-specific short collagen;collagen alpha-1(IX) chain;collagen IX, alpha-1 polypeptide;collagen, type IX, alpha 1;DJ149L1.1.2;EDM6;MED;STL4
- Weitere Details:
- This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20%) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice