GTX53249
FGFR3 antibody [7M13]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX53249
- Anwendung:
- Neutralisation
- Konzentration:
- 200 ug/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Protein G Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rat
- Reaktivitäten:
- Mouse
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Mouse recombinant protein FGF R3
- Klon:
- 7M13
- Synonyme:
- CD333;Fgfr-;Fgfr-3;fibroblast growth factor receptor 3;Flg-2;FR3;HBGF;HBGFR;heparin-binding growth factor receptor;Mfr3;sa;sam3
- Weitere Details:
- This gene encodes a member of the fibroblast growth factor receptor family. Members of this family are highly conserved proteins that differ from one another in their ligand affinities and tissue distribution. A representative protein consists of an extracellular region composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment, and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene may be associated with craniosynostosis and multiple types of skeletal dysplasia. A pseudogene of this gene is located on chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2011]
- Versandbedingungen:
- Blue Ice