Legumain antibody [46I3]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX53080
Zusätzliche Namen:: AEP , LGMN , LGMN1 , PRSC1 , legumain , Legumain
Anwendung:: ELISA, WB
Konzentration:: 200 ug/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, no preservatives.
Immunogen:: Recombinant Human Legumain
Klon:: 46I3
Uniprot:: Q99538
Synonyme:: AEP;asparaginyl endopeptidase;cysteine protease 1;legumain;LGMN1;protease, cysteine 1;protease, cysteine, 1 (legumain);PRSC1
Weitere Details:: This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008]

Versandbedingungen:: Blue Ice