GTX52966
DYNLL1 antibody [9S2]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX52966
- Zusätzliche Namen:
- DLC1 , DLC8 , DNCL1 , DNCLC1 , DYNLL1 , LC8 , LC8a , PIN , dynein light chain LC8type 1 , hdlc1 , dynein light chain LC8-type 1
- Anwendung:
- WB
- Konzentration:
- 500 ug/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein G Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- The immunogen sequence is the full length 89 a.a. of human DYNLL1.
- Klon:
- 9S2
- Uniprot:
- P63167
- Synonyme:
- 8 kDa dynein light chain;cytoplasmic dynein light polypeptide;DLC1;DLC8;DNCL1;DNCLC1;dynein light chain 1, cytoplasmic;Dynein light chain LC8-type 1;dynein, cytoplasmic, light polypeptide 1;hdlc1;LC8;LC8a;PIN;protein inhibitor of neuronal nitric oxide synthase
- Weitere Details:
- Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice