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GTX52821

IL15 antibody [13S34]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX52821
Zusätzliche Namen:
IL15 , interleukin 15
Anwendung:
WB, Neutralisation
Konzentration:
500 ug/ml
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein G Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human
Buffer:
PBS, no preservatives.
Immunogen:
Human recombinant IL-15
Klon:
13S34
Uniprot:
P40933
Synonyme:
IL-15;interleukin-15
Weitere Details:
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
Versandbedingungen:
Blue Ice