GTX52771
CD130 antibody [9X23]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX52771
- Zusätzliche Namen:
- CD130 , CDW130 , GP130 , IL6RB , IL6ST , interleukin 6 signal transducer , gp130
- Anwendung:
- WB
- Konzentration:
- 500 ug/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein G Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Human recombinant gp130
- Klon:
- 9X23
- Uniprot:
- P40189
- Synonyme:
- CD130;CD130 antigen;CDW130;GP130;gp130 of the rheumatoid arthritis antigenic peptide-bearing soluble form;gp130, oncostatin M receptor;HIES4;IL-6 receptor subunit beta;IL-6R subunit beta;IL-6RB;interleukin receptor beta chain;interleukin-6 receptor subunit beta;interleukin-6 signal transducer;membrane glycoprotein 130;membrane glycoprotein gp130;oncostatin-M receptor subunit alpha;sGP130
- Weitere Details:
- The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]
- Versandbedingungen:
- Blue Ice