GTX52512
CCR1 antibody [7B17]
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX52512
- Zusätzliche Namen:
- CC motif chemokine receptor 1 , CCR1 , CD191 , CKR1 , CMKBR1 , HM145 , MIP1aR , SCYAR1 , C-C motif chemokine receptor 1
- Anwendung:
- Flow Cytometry, IHC-P
- Konzentration:
- 500 ug/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Protein G Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Mouse
- Reaktivitäten:
- Human
- Buffer:
- PBS, no preservatives.
- Immunogen:
- Human CCR1 transfected 293 cells
- Klon:
- 7B17
- Uniprot:
- P32246
- Synonyme:
- C-C chemokine receptor type 1;C-C CKR-1;CC-CKR-1;CCR-1;CD191;chemokine (C-C motif) receptor 1;CKR-1;CKR1;CMKBR1;HM145;LD78 receptor;macrophage inflammatory protein 1-alpha receptor;MIP-1alpha-R;MIP1aR;RANTES receptor;RANTES-R;SCYAR1
- Weitere Details:
- This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008]
- Versandbedingungen:
- Blue Ice