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GTX52486

TIMP1 antibody [4A16]

Eine Lieferung in diese Region ist nicht möglich.

SKU:
GTX52486
Zusätzliche Namen:
CLGI , EPA , EPO , HCI , TIMP , TIMP metallopeptidase inhibitor 1 , TIMP1
Anwendung:
WB, IHC-P
Physischer Zustand:
Liquid
Spezies-Reaktivität:
Human
Aufreinigung:
Protein G Purified
Lagerbedingungen:
-20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:
Genetex
Host:
Mouse
Reaktivitäten:
Human
Buffer:
PBS, no preservatives.
Immunogen:
Human recombinant TIMP-1 protein
Klon:
4A16
Uniprot:
P01033
Synonyme:
CLGI;collagenase inhibitor;EPA;epididymis secretory sperm binding protein;EPO;erythroid potentiating activity;Erythroid-potentiating activity;fibroblast collagenase inhibitor;HCI;metalloproteinase inhibitor 1;TIMP;TIMP-1;tissue inhibitor of metalloproteinases 1
Weitere Details:
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction. [provided by RefSeq, Jul 2008]
Versandbedingungen:
Blue Ice