TIE1 antibody [12D9]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX52470
Zusätzliche Namen:: JTK14 , TIE , TIE1 , tyrosine kinase with immunoglobulin like and EGF like domains 1
Anwendung:: WB, IHC-P
Konzentration:: 200 ug/ml
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Protein G Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, no preservatives.
Immunogen:: hTie1 extracellular domain
Klon:: 12D9
Uniprot:: P35590
Synonyme:: JTK14;LMPHM11;TIE;tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1;tyrosine-protein kinase receptor Tie-1
Weitere Details:: This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]