GTX50886
Rad9 (phospho Ser277) antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX50886
- Zusätzliche Namen:
- RAD9 checkpoint clamp component A , RAD9
- Anwendung:
- WB, IHC-P
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified; Protein A Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 0.09% Sodium azide.
- Immunogen:
- KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S277 of human RAD9.
- Uniprot:
- Q99638
- Synonyme:
- cell cycle checkpoint control protein RAD9A;DNA repair exonuclease rad9 homolog A;hRAD9;RAD9;RAD9 homolog A
- Weitere Details:
- This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
- Versandbedingungen:
- Blue Ice