GTX50653
eIF4G antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX50653
- Zusätzliche Namen:
- eukaryotic translation initiation factor 4 gamma 1 , EIF-4G1 , EIF4F , EIF4G , EIF4GI , P220 , PARK18
- Anwendung:
- WB, IHC-P, IF, ICC
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Peptide sequence around aa.1229~1233 (P-V-S-P-L) derived from human eIF4G.
- Uniprot:
- Q04637
- Synonyme:
- eIF-4-gamma 1;EIF-4G1;EIF4-gamma;EIF4F;EIF4G;EIF4GI;eucaryotic translation initiation factor 4G;eukaryotic translation initiation factor 4 gamma 1;P220;PARK18
- Weitere Details:
- The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. [provided by RefSeq, Aug 2010]
- Versandbedingungen:
- Blue Ice