GTX50502
Cofilin antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX50502
- Zusätzliche Namen:
- cofilin 1 , CFL , HEL-S-15 , cofilin
- Anwendung:
- WB, IHC-P
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
- Immunogen:
- Peptide sequence around aa. 1~5 (M-A-S-G-V) derived from human Cofilin.
- Uniprot:
- P23528
- Synonyme:
- 18 kDa phosphoprotein;CFL;cofilin;cofilin 1 (non-muscle);cofilin-1;Cofilin, non-muscle isoform;epididymis secretory protein Li 15;HEL-S-15;p18
- Weitere Details:
- The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004]
- Versandbedingungen:
- Blue Ice