CHD4 antibody [5F1-A11-C9]

Eine Lieferung in diese Region ist nicht möglich.

SKU:: GTX49139
Zusätzliche Namen:: chromodomain helicase DNA binding protein 4 , CHD-4 , Mi-2b , Mi2-BETA , SIHIWES
Anwendung:: WB
Physischer Zustand:: Liquid
Spezies-Reaktivität:: Human
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
Hersteller:: Genetex
Host:: Mouse
Reaktivitäten:: Human
Buffer:: PBS, 0.5% BSA, 50% glycerol, 0.02% Sodium azide.
Immunogen:: Purified recombinant human CHD4 protein fragments expressed in E.coli.
Klon:: 5F1-A11-C9
Uniprot:: Q14839
Synonyme:: ATP-dependent helicase CHD4;CHD-4;chromodomain-helicase-DNA-binding protein 4;Mi-2 autoantigen 218 kDa protein;Mi-2b;Mi2-BETA;SIHIWES
Weitere Details:: The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]