GTX48750
LDB1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX48750
- Zusätzliche Namen:
- LIM domain binding 1 , CLIM2 , NLI
- Anwendung:
- ChIP, ELISA, WB
- Konzentration:
- 1.8 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to a C-Terminal region of mouse LDB1 protein.
- Uniprot:
- P70662
- Synonyme:
- carboxyl-terminal LIM domain-binding protein 2;CLI;CLIM2;LIM domain-binding factor CLIM2;LIM domain-binding protein 1;NLI;nuclear LIM interactor
- Weitere Details:
- LDB1 is also known as CLIM 2, LIM Domain Binding 1, NLI and Nuclear LIM Domain Interactor. The LIM-domain binding protein binds to the LIM domain of LIM homeodomain proteins which are transcriptional regulators of development. Nuclear LIM interactor (NLI) / LIM domain-binding protein 1 (LDB1) is located in the nuclei of neuronal cells during development, it is co-expressed with Isl1 in early motor neuron differentiation and has a suggested role in the Isl1 dependent development of motor neurons. It is suggested that these proteins act synergistically to enhance transcriptional efficiency by acting as co-factors for LIM homeodomain and Otx class transcription factors, both of which have essential roles in development.
- Versandbedingungen:
- Blue Ice