GTX48720
Trkct1 antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX48720
- Zusätzliche Namen:
- neurotrophic tyrosine kinase, receptor, type 3 , AW125844 , Ntrk3_tv3 , TrkC
- Anwendung:
- ELISA, WB, IP
- Konzentration:
- 1 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Human, Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Synthetic peptide corresponding to amino acids near the carboxyl terminus of mouse TrkCT1 protein.
- Uniprot:
- Q6VNS1
- Synonyme:
- AW125844;GP145-TrkC;Neurotrophic tyrosine kinase receptor type 3;neurotrophin-3;NT-3 growth factor receptor;Ntrk3_tv3;Trk;trk-C;TrkC;trkC tyrosine kinase
- Weitere Details:
- TrkCT1, also named neurotrophic tyrosine kinase receptor type 3 (Ntrk3) non-catalytic isoform 2, is a non-catalytic isoform of TrkC, the high affinity receptor for Neurotrophin-3 (NT-3). This isoform lacks the kinase domain that is responsible for signaling by the full-length isoform. TrkCT1 is the product of an alternative splicing of Ntrk3 that leaves the extracellular and transmembrane domains intact but includes a shorter intracellular domain encoded by exons 13b and 14b. Recent studies indicate that the short cytoplasmic tail binds the scaffold protein Tamalin in a ligand-dependent manner and further activates the Arf6-Rac1 signaling pathway (Esteban et al., 2006).
- Versandbedingungen:
- Blue Ice