GTX48705
C-Myb antibody
Eine Lieferung in diese Region ist nicht möglich.
- SKU:
- GTX48705
- Zusätzliche Namen:
- myeloblastosis oncogene , AI550390 , M16449 , c-myb
- Anwendung:
- ELISA, IHC, WB
- Konzentration:
- 1.51 mg/ml
- Physischer Zustand:
- Liquid
- Spezies-Reaktivität:
- Mouse
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., 2-8[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted., -20[o]C/-70[o]C Aliquot. Avoid freeze/thaw cycles. Store undiluted.
- Hersteller:
- Genetex
- Host:
- Rabbit
- Reaktivitäten:
- Mouse
- Buffer:
- 20mM Potassium Phosphate, 150mM NaCl, 0.01% Sodium azide.
- Immunogen:
- Peptide corresponding to an internal portion of mouse c-Myb protein.
- Uniprot:
- P06876
- Synonyme:
- AI550390;c-myb;gag-myb protein;M16449;myb proto-oncogene protein;myeloblastosis proto-oncogene product;proto-oncogene c-Myb;transcriptional activator Myb;tumor-specific myb protein
- Weitere Details:
- The transcription factor c-Myb plays an important role in the development of all hematopoietic lineages during definitive hematopoiesis. Its critical role in hematopoiesis has been first demonstrated in experiments with targeted disruption of the c-Myb gene where deletion of both alleles of the c-Myb gene was embryonally lethal due to severe anemia. c-Myb is a short-lived sequence specific DNA-binding protein that regulates transcription of several important genes involved directly in cellular processes such as proliferation, differentiation, and apoptosis. Post-translational modifications such as phosphorylation, acetylation, ubiquitination, and conjugation of SUMO proteins are crucial for modulation of the transactivation activity of c-Myb.
- Versandbedingungen:
- Blue Ice